Solveig Tiepolt Selected Research

fluoronorchloroepibatidine

1/2021	(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls.
2/2018	Exploring the Metabolism of (+)-[18F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study.
12/2016	Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results.

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Solveig Tiepolt Research Topics

Disease

20	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2013
11	Dementia (Dementias) 01/2022 - 06/2016
5	Cognitive Dysfunction 01/2022 - 01/2015
4	Atrophy 11/2016 - 01/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2019
2	Disease Progression 01/2022 - 01/2018
1	Pulmonary Arterial Hypertension 01/2021
1	Pulmonary Hypertension 01/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2021
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 11/2019
1	Movement Disorders (Movement Disorder) 07/2019
1	Frontotemporal Dementia (Semantic Dementia) 01/2019
1	Amyloid Plaque 11/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2017
1	Atherosclerosis 07/2017
1	Tobacco Use Disorder (Nicotine Dependence) 09/2015
1	Depressive Disorder (Melancholia) 09/2015
1	Neurobehavioral Manifestations 08/2015
1	Infections 01/2015

Drug/Important Bio-Agent (IBA)

13	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2013
11	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2015
6	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 01/2018 - 01/2013
3	Amyloid beta-PeptidesIBA 01/2022 - 08/2015
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2021 - 09/2015
3	fluoronorchloroepibatidineIBA 01/2021 - 12/2016
2	Cholinergic Agents (Cholinergics)IBA 01/2022 - 01/2018
1	Cholinergic ReceptorsIBA 01/2022
1	EnzymesIBA 01/2022
1	3- (1,4- diazabicyclo(3.2.2)nonan- 4- yl)- 6- fluorodibenzo(b,d)thiophene 5,5-dioxideIBA 01/2022
1	LigandsIBA 01/2021
1	3- amino- 4- (2- dimethylaminomethylphenylsulfanyl)benzonitrileIBA 01/2021
1	pro-brain natriuretic peptide (1-76)IBA 01/2021
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2021
1	IronIBA 10/2020
1	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 11/2019
1	Biological ProductsIBA 07/2019
1	PrionsIBA 07/2019
1	Citalopram FDA LinkGeneric 01/2019
1	Cholinesterases (Cholinesterase)IBA 01/2018
1	Pharmaceutical PreparationsIBA 01/2018
1	Peptides (Polypeptides)IBA 07/2017
1	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 08/2016
1	Indicators and Reagents (Reagents)IBA 08/2015
1	Pemetrexed (MTA)FDA Link 01/2015

Therapy/Procedure

2	Therapeutics 01/2022 - 01/2018
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2015
1	Arthroplasty 01/2015
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2015